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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T24438 | MDK5466 | MDK-5466,MDK 5466,E21,Flt3-IN-III,Flt3 Inhibitor III | |
MDK5466 is an Flt3 inhibitor that acts by preventing glutamate-induced cell death. | |||
T2677 | Crenolanib | ARO 002,CP-868596 | FLT , PDGFR , Autophagy |
Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM). | |||
T6479 | Dovitinib lactate hydrate | Dovitinib (TKI258) Lactate,Dovitinib Lactate,TKI258 | VEGFR , FGFR , FLT , PDGFR , c-Kit |
Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) R... | |||
T6289 | Dovitinib | TKI258,CHIR-258 | VEGFR , FGFR , FLT , PDGFR , c-Kit |
Dovitinib (CHIR-258) (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 nM), also effective to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs (IC50: 8-13 nM), less potent to E... | |||
T71400 | Quizartinib HCl | ||
Quizartinib, also know as AC220 and AC010220, is an orally available FLT3 / STK1 inhibitor with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III recept... | |||
T6193 | Dovitinib Dilactic Acid | Dovitinib (TKI-258) Dilactic Acid,TKI258 Dilactic acid | VEGFR , FGFR , FLT , c-Kit |
Dovitinib Dilactic Acid (Dovitinib (TKI-258) Dilactic Acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FG... |